The endothelium is a layer of uniformly sized cells with hexagonal shape, which acts as a semipermeable membrane that allows the flow of aqueous humour that supplies the cornea with glucose and other nutrients. Its main function is removing water from the cornea to maintain its transparency.

In the event of endothelial graft failure, it must be replaced with surgery.

The techniques that are currently available are:

DSAEK surgery 

  • DSAEK surgery (Descemet Stripping with Automated Endothelial Keratoplasty) consists in replacing the two far rear layers of the cornea (Descemet and endothelium), which are in direct contact with the aqueous humour and the front chamber of the eye. The endothelium is a layer of uniformly sized cells with hexagonal shape, which acts as a semipermeable membrane that allows the flow of aqueous humour that supplies the cornea with glucose and other nutrients. Currently, transplantation of this layer allows for a faster recovery and better forecast of refractive results (astigmatism). First and foremost, it is much more safe (less complications) than other total transplant methods, as the entire cornea does not need to be removed and there is no open cut. This reduces the number of check-ups and any rejection processes can be controlled much easier.

DMEK (Descemet Membrane Endothelial Keratoplasty)

This is a new procedure for the partial transplant of the cornea. Only the endothelial cell layer is implanted.

DALK technique (Deep Anterior Lamellar Keratoplasty)

Only the furthest layer of the cornea is transplanted, leaving the internal part untouched.

Penetrating keratoplasty

This consists of replacing the entire cornea with the cornea of a donor.

Our team will help you to find the best solution